Caroline Mvilongo Tsimi
Yaounde Central Hospital
Cameroon
Title: Bilateral retinoblastoma with extra-retinal diffusion: 2 cases series
Biography
Biography: Caroline Mvilongo Tsimi
Abstract
Introduction: Retinoblastoma is an embryonal tumor of neuroectodermal origin, highly malignant affecting the young child and the infant. It is bilateral in 40% of cases. We report 2 clinical cases of bilateral retinoblastoma with extra-retinal diffusion which is a poor prognosis factor. Case 1: DW, 20 months brought in our ophthalmology service in 2009 with a tumor of the left eye since one month with a past history of leucocoria since birth. At the ophthalmology exam, he was classified at stage V of Reese- Ellsworth for the contro-lateral right eye and orbital extension of the left eye. He has been enucleated for the left eye and received 3 doses of chemotherapy. The patient was lost of view 2 months after the surgery. Case 2: H O, 3 years centrafican refugee referred in our ophthalmology service on June 2015 for the care of a tumor of the right eye since 3 months. She had a leucocoria in the right eye since one year; with past history of 1st degree consanguinity. The ophthalmology exam showed a great tumor with necrosis and inflammation of the right eye. At the left eye, sub-retinal mass with retinal detachment stage-V of Reese- Ellsworth, she has received neoadjuvant chemotherapy and exenteration of the right eye. She died few hours after the surgery. These 2 cases have been seen late in an appropriate ophthalmology unit. The prognosis was poor because of the extra retinal diffusion of the tumor.
