Global Pediatric Ophthalmology Congress

Biography

Biography: Celso Marcelo Cunha

Abstract

PURPOSE: To compare the efficacy of 0.025% atropine eye drop in children for the control of myopia with and without photosensitive lens. METHODS: This was a prospective study of sixty children, aged 6 to 12, with spherical equivalent refractive error of -1.00 to -6.00 diopters (D) and astigmatism of -1.00 D or smaller. Children were randomly assigned into two groups in a 1:1 ratio of either anti-reflective coating lens (group 1) or photosensitive lens (group 2). Both groups used 0.025% atropine, once-nightly dosing to both eyes for 1 year. Cycloplegic refraction, axial length, and keratometry were noted at the baseline and 1 year later. In terms of corneal topography, only regular astigmatism was accepted. Student's t test was used to compare the two groups. RESULTS: The age mean and SD for the two groups were 8.2 +/- 1.7 and 8.3 +/- 1.7 years; the initial refractive errors were -3.63 +/- 1.21 D and -3.60 +/- 1.38 D in groups 1 and 2, respectively. Myopic progression was significantly less (P = 0.0007) in group 1 (-0.19 +/- 0.14 D) than in group 2 (-0.32 +/- 0.13 D). Axial length increase was also significantly smaller (P = 0.001) in group 1(0.11 +/- 0.08 mm) than in group 2 (0.21 +/- 0.11 mm). There were no significant statistical differences in relation to keratometry between groups. CONCLUSION: Topical 0.025% atropine eye drops is more effective without photosensitive lens for retarding myopic progression in moderate myopia. However, it is necessary the usage of multilayer anti-refrective coating lens for preventing glare. Furthermore, a larger scale randomized controlled study with longer follow-up seems warranted.